The Ontario Neurodegenerative Disease Research Initiative (ONDRI).
Identifieur interne : 000015 ( Main/Exploration ); précédent : 000014; suivant : 000016The Ontario Neurodegenerative Disease Research Initiative (ONDRI).
Auteurs : Sali M K. Farhan [Canada] ; Robert Bartha [Canada] ; Sandra E. Black [Canada] ; Dale Corbett [Canada] ; Elizabeth Finger [Canada] ; Morris Freedman [Canada] ; Barry Greenberg [Canada] ; David A. Grimes [Canada] ; Robert A. Hegele [Canada] ; Chris Hudson [Canada] ; Peter W. Kleinstiver [Canada] ; Anthony E. Lang [Canada] ; Mario Masellis [Canada] ; William E. Mcilroy [Canada] ; Paula M. Mclaughlin [Canada] ; Manuel Montero-Odasso [Canada] ; David G. Munoz [Canada] ; Douglas P. Munoz [Canada] ; Stephen Strother [Canada] ; Richard H. Swartz [Canada] ; Sean Symons [Canada] ; Maria Carmela Tartaglia [Canada] ; Lorne Zinman [Canada] ; Michael J. Strong [Canada]Source :
- The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques [ 0317-1671 ] ; 2017.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Neurodegenerative Diseases.
- Humans, Longitudinal Studies, Ontario.
Abstract
Because individuals develop dementia as a manifestation of neurodegenerative or neurovascular disorder, there is a need to develop reliable approaches to their identification. We are undertaking an observational study (Ontario Neurodegenerative Disease Research Initiative [ONDRI]) that includes genomics, neuroimaging, and assessments of cognition as well as language, speech, gait, retinal imaging, and eye tracking. Disorders studied include Alzheimer's disease, amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease, and vascular cognitive impairment. Data from ONDRI will be collected into the Brain-CODE database to facilitate correlative analysis. ONDRI will provide a repertoire of endophenotyped individuals that will be a unique, publicly available resource.
DOI: 10.1017/cjn.2016.415
PubMed: 28003035
Affiliations:
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Le document en format XML
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Farhan</name><affiliation wicri:level="3"><nlm:affiliation>1Department of Biochemistry,Schulich School of Medicine & Dentistry,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>1Department of Biochemistry,Schulich School of Medicine & Dentistry,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Bartha, Robert" sort="Bartha, Robert" uniqKey="Bartha R" first="Robert" last="Bartha">Robert Bartha</name><affiliation wicri:level="3"><nlm:affiliation>2Robarts Research Institute,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>2Robarts Research Institute,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Black, Sandra E" sort="Black, Sandra E" uniqKey="Black S" first="Sandra E" last="Black">Sandra E. Black</name><affiliation wicri:level="1"><nlm:affiliation>4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Corbett, Dale" sort="Corbett, Dale" uniqKey="Corbett D" first="Dale" last="Corbett">Dale Corbett</name><affiliation wicri:level="1"><nlm:affiliation>6Department of Cellular and Molecular Medicine, Faculty of Medicine,University of Ottawa,Ottawa,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>6Department of Cellular and Molecular Medicine, Faculty of Medicine,University of Ottawa,Ottawa</wicri:regionArea><wicri:noRegion>Ottawa</wicri:noRegion></affiliation></author><author><name sortKey="Finger, Elizabeth" sort="Finger, Elizabeth" uniqKey="Finger E" first="Elizabeth" last="Finger">Elizabeth Finger</name><affiliation wicri:level="3"><nlm:affiliation>7Department of Clinical Neurological Sciences,Schulich School of Medicine & Dentistry,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>7Department of Clinical Neurological Sciences,Schulich School of Medicine & Dentistry,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Freedman, Morris" sort="Freedman, Morris" uniqKey="Freedman M" first="Morris" last="Freedman">Morris Freedman</name><affiliation wicri:level="4"><nlm:affiliation>8Department of Medicine (Neurology),Baycrest Health Sciences and University of Toronto,Toronto,Ontario,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>8Department of Medicine (Neurology),Baycrest Health Sciences and University of Toronto,Toronto,Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Greenberg, Barry" sort="Greenberg, Barry" uniqKey="Greenberg B" first="Barry" last="Greenberg">Barry Greenberg</name><affiliation wicri:level="1"><nlm:affiliation>10Toronto Dementia Research Alliance,University Health Network,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>10Toronto Dementia Research Alliance,University Health Network,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Grimes, David A" sort="Grimes, David A" uniqKey="Grimes D" first="David A" last="Grimes">David A. 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Kleinstiver</name><affiliation wicri:level="3"><nlm:affiliation>13Schulich School of Medicine & Dentistry,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>13Schulich School of Medicine & Dentistry,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name><affiliation wicri:level="1"><nlm:affiliation>14Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J Safra Program in Parkinson's Disease,Toronto Western Hospital and the Department of Medicine,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>14Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J Safra Program in Parkinson's Disease,Toronto Western Hospital and the Department of Medicine,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Masellis, Mario" sort="Masellis, Mario" uniqKey="Masellis M" first="Mario" last="Masellis">Mario Masellis</name><affiliation wicri:level="1"><nlm:affiliation>4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Mcilroy, William E" sort="Mcilroy, William E" uniqKey="Mcilroy W" first="William E" last="Mcilroy">William E. Mcilroy</name><affiliation wicri:level="1"><nlm:affiliation>15Department of Kinesiology,University of Waterloo,Waterloo,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>15Department of Kinesiology,University of Waterloo,Waterloo</wicri:regionArea><wicri:noRegion>Waterloo</wicri:noRegion></affiliation></author><author><name sortKey="Mclaughlin, Paula M" sort="Mclaughlin, Paula M" uniqKey="Mclaughlin P" first="Paula M" last="Mclaughlin">Paula M. 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Munoz</name><affiliation wicri:level="1"><nlm:affiliation>17Keenan Research Centre for Biomedical Science of St. Michael's Hospital,Laboratory Medicine and Pathobiology,University of Toronto,Division of Pathology,St. Michael's Hospital,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>17Keenan Research Centre for Biomedical Science of St. Michael's Hospital,Laboratory Medicine and Pathobiology,University of Toronto,Division of Pathology,St. Michael's Hospital,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Munoz, Douglas P" sort="Munoz, Douglas P" uniqKey="Munoz D" first="Douglas P" last="Munoz">Douglas P. Munoz</name><affiliation wicri:level="1"><nlm:affiliation>18Centre for Neuroscience Studies,Queen's University,Kingston,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>18Centre for Neuroscience Studies,Queen's University,Kingston</wicri:regionArea><wicri:noRegion>Kingston</wicri:noRegion></affiliation></author><author><name sortKey="Strother, Stephen" sort="Strother, Stephen" uniqKey="Strother S" first="Stephen" last="Strother">Stephen Strother</name><affiliation wicri:level="1"><nlm:affiliation>19Rotman Research Institute,Baycrest,Department of Medical Biophysics,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>19Rotman Research Institute,Baycrest,Department of Medical Biophysics,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Swartz, Richard H" sort="Swartz, Richard H" uniqKey="Swartz R" first="Richard H" last="Swartz">Richard H. Swartz</name><affiliation wicri:level="1"><nlm:affiliation>20Department of Medicine (Neurology),L.C. Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,Sunnybrook Health Sciences Centre,Institute of Medical Science, Faculty of Medicine,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>20Department of Medicine (Neurology),L.C. Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,Sunnybrook Health Sciences Centre,Institute of Medical Science, Faculty of Medicine,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Symons, Sean" sort="Symons, Sean" uniqKey="Symons S" first="Sean" last="Symons">Sean Symons</name><affiliation wicri:level="1"><nlm:affiliation>21Department of Medical Imaging,Sunnybrook Health Sciences Centre,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>21Department of Medical Imaging,Sunnybrook Health Sciences Centre,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Tartaglia, Maria Carmela" sort="Tartaglia, Maria Carmela" uniqKey="Tartaglia M" first="Maria Carmela" last="Tartaglia">Maria Carmela Tartaglia</name><affiliation wicri:level="1"><nlm:affiliation>22Division of Neurology and Department of Medicine,University of Toronto. Tanz Centre for Research in Neurodegenerative Diseases,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>22Division of Neurology and Department of Medicine,University of Toronto. 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Strong</name><affiliation wicri:level="3"><nlm:affiliation>2Robarts Research Institute,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>2Robarts Research Institute,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28003035</idno><idno type="pmid">28003035</idno><idno type="doi">10.1017/cjn.2016.415</idno><idno type="wicri:Area/PubMed/Corpus">000044</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000044</idno><idno type="wicri:Area/PubMed/Curation">000044</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000044</idno><idno type="wicri:Area/PubMed/Checkpoint">000044</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000044</idno><idno type="wicri:Area/Ncbi/Merge">002173</idno><idno type="wicri:Area/Ncbi/Curation">002173</idno><idno type="wicri:Area/Ncbi/Checkpoint">002173</idno><idno type="wicri:doubleKey">0317-1671:2017:Farhan S:the:ontario:neurodegenerative</idno><idno type="wicri:Area/Main/Merge">000015</idno><idno type="wicri:Area/Main/Curation">000015</idno><idno type="wicri:Area/Main/Exploration">000015</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The Ontario Neurodegenerative Disease Research Initiative (ONDRI).</title><author><name sortKey="Farhan, Sali M K" sort="Farhan, Sali M K" uniqKey="Farhan S" first="Sali M K" last="Farhan">Sali M K. Farhan</name><affiliation wicri:level="3"><nlm:affiliation>1Department of Biochemistry,Schulich School of Medicine & Dentistry,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>1Department of Biochemistry,Schulich School of Medicine & Dentistry,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Bartha, Robert" sort="Bartha, Robert" uniqKey="Bartha R" first="Robert" last="Bartha">Robert Bartha</name><affiliation wicri:level="3"><nlm:affiliation>2Robarts Research Institute,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>2Robarts Research Institute,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Black, Sandra E" sort="Black, Sandra E" uniqKey="Black S" first="Sandra E" last="Black">Sandra E. Black</name><affiliation wicri:level="1"><nlm:affiliation>4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Corbett, Dale" sort="Corbett, Dale" uniqKey="Corbett D" first="Dale" last="Corbett">Dale Corbett</name><affiliation wicri:level="1"><nlm:affiliation>6Department of Cellular and Molecular Medicine, Faculty of Medicine,University of Ottawa,Ottawa,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>6Department of Cellular and Molecular Medicine, Faculty of Medicine,University of Ottawa,Ottawa</wicri:regionArea><wicri:noRegion>Ottawa</wicri:noRegion></affiliation></author><author><name sortKey="Finger, Elizabeth" sort="Finger, Elizabeth" uniqKey="Finger E" first="Elizabeth" last="Finger">Elizabeth Finger</name><affiliation wicri:level="3"><nlm:affiliation>7Department of Clinical Neurological Sciences,Schulich School of Medicine & Dentistry,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>7Department of Clinical Neurological Sciences,Schulich School of Medicine & Dentistry,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Freedman, Morris" sort="Freedman, Morris" uniqKey="Freedman M" first="Morris" last="Freedman">Morris Freedman</name><affiliation wicri:level="4"><nlm:affiliation>8Department of Medicine (Neurology),Baycrest Health Sciences and University of Toronto,Toronto,Ontario,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>8Department of Medicine (Neurology),Baycrest Health Sciences and University of Toronto,Toronto,Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Greenberg, Barry" sort="Greenberg, Barry" uniqKey="Greenberg B" first="Barry" last="Greenberg">Barry Greenberg</name><affiliation wicri:level="1"><nlm:affiliation>10Toronto Dementia Research Alliance,University Health Network,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>10Toronto Dementia Research Alliance,University Health Network,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Grimes, David A" sort="Grimes, David A" uniqKey="Grimes D" first="David A" last="Grimes">David A. Grimes</name><affiliation wicri:level="1"><nlm:affiliation>11Department of Medicine,The Ottawa Hospital, Faculty of Medicine,University of Ottawa,Ottawa,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>11Department of Medicine,The Ottawa Hospital, Faculty of Medicine,University of Ottawa,Ottawa</wicri:regionArea><wicri:noRegion>Ottawa</wicri:noRegion></affiliation></author><author><name sortKey="Hegele, Robert A" sort="Hegele, Robert A" uniqKey="Hegele R" first="Robert A" last="Hegele">Robert A. Hegele</name><affiliation wicri:level="3"><nlm:affiliation>1Department of Biochemistry,Schulich School of Medicine & Dentistry,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>1Department of Biochemistry,Schulich School of Medicine & Dentistry,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Hudson, Chris" sort="Hudson, Chris" uniqKey="Hudson C" first="Chris" last="Hudson">Chris Hudson</name><affiliation wicri:level="1"><nlm:affiliation>12School of Optometry & Vision Science,University of Waterloo,Waterloo,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>12School of Optometry & Vision Science,University of Waterloo,Waterloo</wicri:regionArea><wicri:noRegion>Waterloo</wicri:noRegion></affiliation></author><author><name sortKey="Kleinstiver, Peter W" sort="Kleinstiver, Peter W" uniqKey="Kleinstiver P" first="Peter W" last="Kleinstiver">Peter W. Kleinstiver</name><affiliation wicri:level="3"><nlm:affiliation>13Schulich School of Medicine & Dentistry,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>13Schulich School of Medicine & Dentistry,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name><affiliation wicri:level="1"><nlm:affiliation>14Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J Safra Program in Parkinson's Disease,Toronto Western Hospital and the Department of Medicine,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>14Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J Safra Program in Parkinson's Disease,Toronto Western Hospital and the Department of Medicine,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Masellis, Mario" sort="Masellis, Mario" uniqKey="Masellis M" first="Mario" last="Masellis">Mario Masellis</name><affiliation wicri:level="1"><nlm:affiliation>4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Mcilroy, William E" sort="Mcilroy, William E" uniqKey="Mcilroy W" first="William E" last="Mcilroy">William E. Mcilroy</name><affiliation wicri:level="1"><nlm:affiliation>15Department of Kinesiology,University of Waterloo,Waterloo,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>15Department of Kinesiology,University of Waterloo,Waterloo</wicri:regionArea><wicri:noRegion>Waterloo</wicri:noRegion></affiliation></author><author><name sortKey="Mclaughlin, Paula M" sort="Mclaughlin, Paula M" uniqKey="Mclaughlin P" first="Paula M" last="Mclaughlin">Paula M. Mclaughlin</name><affiliation wicri:level="3"><nlm:affiliation>13Schulich School of Medicine & Dentistry,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>13Schulich School of Medicine & Dentistry,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Montero Odasso, Manuel" sort="Montero Odasso, Manuel" uniqKey="Montero Odasso M" first="Manuel" last="Montero-Odasso">Manuel Montero-Odasso</name><affiliation wicri:level="3"><nlm:affiliation>16Gait and Brain Lab,Department of Medicine (Geriatrics) and Epidemiology and Biostatistics,Schulich School of Medicine & Dentistry,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>16Gait and Brain Lab,Department of Medicine (Geriatrics) and Epidemiology and Biostatistics,Schulich School of Medicine & Dentistry,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Munoz, David G" sort="Munoz, David G" uniqKey="Munoz D" first="David G" last="Munoz">David G. Munoz</name><affiliation wicri:level="1"><nlm:affiliation>17Keenan Research Centre for Biomedical Science of St. Michael's Hospital,Laboratory Medicine and Pathobiology,University of Toronto,Division of Pathology,St. Michael's Hospital,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>17Keenan Research Centre for Biomedical Science of St. Michael's Hospital,Laboratory Medicine and Pathobiology,University of Toronto,Division of Pathology,St. Michael's Hospital,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Munoz, Douglas P" sort="Munoz, Douglas P" uniqKey="Munoz D" first="Douglas P" last="Munoz">Douglas P. Munoz</name><affiliation wicri:level="1"><nlm:affiliation>18Centre for Neuroscience Studies,Queen's University,Kingston,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>18Centre for Neuroscience Studies,Queen's University,Kingston</wicri:regionArea><wicri:noRegion>Kingston</wicri:noRegion></affiliation></author><author><name sortKey="Strother, Stephen" sort="Strother, Stephen" uniqKey="Strother S" first="Stephen" last="Strother">Stephen Strother</name><affiliation wicri:level="1"><nlm:affiliation>19Rotman Research Institute,Baycrest,Department of Medical Biophysics,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>19Rotman Research Institute,Baycrest,Department of Medical Biophysics,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Swartz, Richard H" sort="Swartz, Richard H" uniqKey="Swartz R" first="Richard H" last="Swartz">Richard H. Swartz</name><affiliation wicri:level="1"><nlm:affiliation>20Department of Medicine (Neurology),L.C. Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,Sunnybrook Health Sciences Centre,Institute of Medical Science, Faculty of Medicine,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>20Department of Medicine (Neurology),L.C. Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,Sunnybrook Health Sciences Centre,Institute of Medical Science, Faculty of Medicine,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Symons, Sean" sort="Symons, Sean" uniqKey="Symons S" first="Sean" last="Symons">Sean Symons</name><affiliation wicri:level="1"><nlm:affiliation>21Department of Medical Imaging,Sunnybrook Health Sciences Centre,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>21Department of Medical Imaging,Sunnybrook Health Sciences Centre,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Tartaglia, Maria Carmela" sort="Tartaglia, Maria Carmela" uniqKey="Tartaglia M" first="Maria Carmela" last="Tartaglia">Maria Carmela Tartaglia</name><affiliation wicri:level="1"><nlm:affiliation>22Division of Neurology and Department of Medicine,University of Toronto. Tanz Centre for Research in Neurodegenerative Diseases,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>22Division of Neurology and Department of Medicine,University of Toronto. Tanz Centre for Research in Neurodegenerative Diseases,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Zinman, Lorne" sort="Zinman, Lorne" uniqKey="Zinman L" first="Lorne" last="Zinman">Lorne Zinman</name><affiliation wicri:level="1"><nlm:affiliation>4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Strong, Michael J" sort="Strong, Michael J" uniqKey="Strong M" first="Michael J" last="Strong">Michael J. Strong</name><affiliation wicri:level="3"><nlm:affiliation>2Robarts Research Institute,Western University,London,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>2Robarts Research Institute,Western University,London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></analytic><series><title level="j">The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques</title><idno type="ISSN">0317-1671</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Humans</term><term>Longitudinal Studies</term><term>Neurodegenerative Diseases (diagnosis)</term><term>Ontario</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Neurodegenerative Diseases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Longitudinal Studies</term><term>Ontario</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Because individuals develop dementia as a manifestation of neurodegenerative or neurovascular disorder, there is a need to develop reliable approaches to their identification. We are undertaking an observational study (Ontario Neurodegenerative Disease Research Initiative [ONDRI]) that includes genomics, neuroimaging, and assessments of cognition as well as language, speech, gait, retinal imaging, and eye tracking. Disorders studied include Alzheimer's disease, amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease, and vascular cognitive impairment. Data from ONDRI will be collected into the Brain-CODE database to facilitate correlative analysis. ONDRI will provide a repertoire of endophenotyped individuals that will be a unique, publicly available resource.</div></front></TEI><affiliations><list><country><li>Canada</li></country><region><li>Angleterre</li><li>Grand Londres</li><li>Ontario</li></region><settlement><li>Londres</li><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><country name="Canada"><region name="Angleterre"><name sortKey="Farhan, Sali M K" sort="Farhan, Sali M K" uniqKey="Farhan S" first="Sali M K" last="Farhan">Sali M K. Farhan</name></region><name sortKey="Bartha, Robert" sort="Bartha, Robert" uniqKey="Bartha R" first="Robert" last="Bartha">Robert Bartha</name><name sortKey="Black, Sandra E" sort="Black, Sandra E" uniqKey="Black S" first="Sandra E" last="Black">Sandra E. Black</name><name sortKey="Corbett, Dale" sort="Corbett, Dale" uniqKey="Corbett D" first="Dale" last="Corbett">Dale Corbett</name><name sortKey="Finger, Elizabeth" sort="Finger, Elizabeth" uniqKey="Finger E" first="Elizabeth" last="Finger">Elizabeth Finger</name><name sortKey="Freedman, Morris" sort="Freedman, Morris" uniqKey="Freedman M" first="Morris" last="Freedman">Morris Freedman</name><name sortKey="Greenberg, Barry" sort="Greenberg, Barry" uniqKey="Greenberg B" first="Barry" last="Greenberg">Barry Greenberg</name><name sortKey="Grimes, David A" sort="Grimes, David A" uniqKey="Grimes D" first="David A" last="Grimes">David A. Grimes</name><name sortKey="Hegele, Robert A" sort="Hegele, Robert A" uniqKey="Hegele R" first="Robert A" last="Hegele">Robert A. Hegele</name><name sortKey="Hudson, Chris" sort="Hudson, Chris" uniqKey="Hudson C" first="Chris" last="Hudson">Chris Hudson</name><name sortKey="Kleinstiver, Peter W" sort="Kleinstiver, Peter W" uniqKey="Kleinstiver P" first="Peter W" last="Kleinstiver">Peter W. Kleinstiver</name><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name><name sortKey="Masellis, Mario" sort="Masellis, Mario" uniqKey="Masellis M" first="Mario" last="Masellis">Mario Masellis</name><name sortKey="Mcilroy, William E" sort="Mcilroy, William E" uniqKey="Mcilroy W" first="William E" last="Mcilroy">William E. Mcilroy</name><name sortKey="Mclaughlin, Paula M" sort="Mclaughlin, Paula M" uniqKey="Mclaughlin P" first="Paula M" last="Mclaughlin">Paula M. Mclaughlin</name><name sortKey="Montero Odasso, Manuel" sort="Montero Odasso, Manuel" uniqKey="Montero Odasso M" first="Manuel" last="Montero-Odasso">Manuel Montero-Odasso</name><name sortKey="Munoz, David G" sort="Munoz, David G" uniqKey="Munoz D" first="David G" last="Munoz">David G. Munoz</name><name sortKey="Munoz, Douglas P" sort="Munoz, Douglas P" uniqKey="Munoz D" first="Douglas P" last="Munoz">Douglas P. Munoz</name><name sortKey="Strong, Michael J" sort="Strong, Michael J" uniqKey="Strong M" first="Michael J" last="Strong">Michael J. Strong</name><name sortKey="Strother, Stephen" sort="Strother, Stephen" uniqKey="Strother S" first="Stephen" last="Strother">Stephen Strother</name><name sortKey="Swartz, Richard H" sort="Swartz, Richard H" uniqKey="Swartz R" first="Richard H" last="Swartz">Richard H. Swartz</name><name sortKey="Symons, Sean" sort="Symons, Sean" uniqKey="Symons S" first="Sean" last="Symons">Sean Symons</name><name sortKey="Tartaglia, Maria Carmela" sort="Tartaglia, Maria Carmela" uniqKey="Tartaglia M" first="Maria Carmela" last="Tartaglia">Maria Carmela Tartaglia</name><name sortKey="Zinman, Lorne" sort="Zinman, Lorne" uniqKey="Zinman L" first="Lorne" last="Zinman">Lorne Zinman</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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